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UPDATE: CINCINNATI (WLWT) - At least four people are dead – including the gunman -- following what police called an active shooter situation in downtown Cincinnati.

It happened around 9 a.m. Thursday at Fifth Third Center on Walnut Street.

Police said a gunman entered the building through a loading dock and made his way to the lobby of the office building.

Three people were killed by the gunman, officials said, and two others were wounded.

The gunman was confronted by Cincinnati police officers inside of the building, officials said, and a shootout commenced.

The gunman was killed in the incident, police said, although it's unclear if he was shot by police or his own hand.

No officers were injured in the incident, and the gunman's motive remains unclear.

Officials with the Hamilton County Sheriff's Office confirm they are currently searching the home of the now-deceased gunman at his home in North Bend, Ohio. The gunman's name has not been released.

According to officials with University of Cincinnati Medical Center, the hospital received a total of four victims: Three males and one female. Two of those patients are among the dead, officials said, one is in serious condition and the other in critical condition.

"Again, our physicians and staff are focused on caring for the patients and their families. We prepare for situations like these and hope they never happen. Our thoughts and prayers are with the victims, their families and all involved," medical officials said.

The chaos unfolded alongside Fountain Square, the heavily trafficked park at the city's center.

Several nearby buildings were placed on lockdown as the situation unfolded. SWAT teams are continuing to sweep the area to ensure safety and to search for possible additional victims.

Witnesses in the area described a chaotic walk to work, hearing about 10 gunshots ring out during the morning rush.

Sen. Rob Portman has released a brief statement as details develop, saying in part, "My staff and I are following the situation in Cincinnati. If you're downtown, please follow first responder instructions for the safety of everyone involved. Jane and I hope for a peaceful resolution soon."

Officials with Fifth Third bank released a statement in wake of the shooting, saying in part, "Our thoughts and prayers are with everyone caught up in this terrible event. We continue to work with law enforcement as we ensure the safety of our employees and customers. We are grateful for the support and concerns from our neighbors throughout Cincinnati and the country."

This is a developing story and will be updated.