NASHVILLE, Tenn. (AP) - Marcus Mariota threw a 53-yard touchdown pass to Taywan Taylor with 5:29 left , and the Tennessee Titans beat the Indianapolis Colts 36-22 on Monday night to snap an 11-game skid tied for the NFL's longest active losing streak against one team.
Mariota didn't move around much on a cool night after missing a game with a strained left hamstring, but still managed to throw for a season-high 306 yards. He completed each of his three passes on the drive that ended with Taylor's tiebreaking score.
The Titans (3-3) also snapped a two-game skid with the win.
Jacoby Brissett tried to rally the Colts (2-4) to a second straight overtime. But Titans linebacker Wesley Woodyard forced Brissett out of bounds shy of the first down marker on fourth-and-inches with 2:19 left. Coach Chuck Pagano lost his challenge.
Derrick Henry then clinched the win for Tennessee with a 72-yard TD run with 47 seconds left. Henry, the 2015 Heisman Trophy winner, finished with a career-high 131 yards on 19 carries. DeMarco Murray also scored.
The Titans looked like the NFL's worst scoring defense in the first half instead of Indianapolis, with Brissett directing the Colts to a 13-9 halftime lead. John Simon then intercepted Mariota's first pass of the third quarter and returned it 26 yards for a TD.
But the Titans forced the Colts to go three-and-out on three of their first four drives of the second half, and Avery Williamson stripped tight end Jack Doyle of the ball after a catch.