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WATCH: Hoda Kotb, Cyndi Lauper and Sara Bareilles fight pediatric cancer with 'Truly Brave' music video

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As part of TODAY's Shine a Light series, a campaign to support worthy causes throughout the year, Hoda Kotb has chosen to lift the spirits of children with cancer and raise money for pediatric cancer. You can help. Visit to learn more.

It's surprising how cheerful it can be at the Children's Hospital of Philadelphia, but in the battle against pediatric cancer, smiles are as important as drugs and surgery.

That's why Hoda Kotb, herself a breast cancer survivor, felt it was so important to bring a little joy to the children being treated there. So with a little help, she launched "Project Truly Brave": a musical collaboration between Sara Bareilles and Cyndi Lauper starring a beautiful and brave group of kids fighting cancer.

All of the adorable children who helped make the collaboration special appeared on TODAY Thursday, beaming with pride after seeing the video and their performances for the first time.

Lizzy Hennessy is a 9-year-old patient at the hospital who was diagnosed with leukemia this summer.

"We never expected our beautiful, smart athletic daughter to be battling cancer," Lizzy's mom, Mary, told TODAY. "It was a pretty bad summer, but a highlight of it was being involved in Hoda's music video."

Cheyenne is another one of the young patients fighting cancer, and some days she says she wishes she could be invisible. "Because then I could hide easily, so I wouldn't have to take my medicine," she told Hoda.

WATCH MORE| The story behind Hoda, Sara Bareilles and Cyndi Lauper's song collaboration

"There's a lot of pain and suffering in the life of a child with cancer," Dr. Anne Reilly, medical director of the Cancer Center at the CHOP, told TODAY. "Part of what we try to do here is to make it uplifting and make it cheerful."

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